This amazing nutrient reduces Alzheimer`s plaque formation by ninety percent
Originally published February 23 2011
by John Phillip
(NaturalNews) Alzheimer`s disease is a devastating condition that is
characterized by the formation of protein amyloid plaques that attack the neural
synapses and prevent normal chemical and electrical signaling activity in the
brain. Medical researchers aren`t certain if plaque is the cause of Alzheimer`s
disease or a normal byproduct of cellular metabolism that remains behind to
provoke the memory-robbing condition. The British Journal of Pharmacology
provides evidence to explain how plaque is formed in the absence of friendly
endothelial nitric oxide (eNOS) that disrupts blood pressure, lipid levels and
glucose in the brain. Resveratrol can increase eNOS levels in the brain and
lower the impact of deadly plaques seen in Alzheimer`s disease.
Friendly nitric oxide is essential to the proper function of our vascular
system. eNOS allows vessels and arteries to contract and expand so blood can
effectively circulate to deliver nutrients and oxygen throughout the body. When
eNOS production is inhibited, blood pressure rises and problems with blood
glucose and cholesterol metabolism become evident.
A current study in the journal PLoS ONE demonstrates that as plaque begins to
accumulate at the neural synapses, eNOS production declines, compounding the
problem. Free radicals multiply in the brain as a consequence of the increasing
amyloid load and extensive damage to delicate brain structures essential to
cognitive function and memory ensue.
Resveratrol is a natural protective compound found in high concentrations in red
grapes, red wine, purple grape juice, peanuts, and some berries. The nutrient
has been the subject of extensive research as it has been shown to mimic the
effect of caloric restriction known to extend healthy life span. New evidence
explains how resveratrol can reduce amyloid plaque burden in the aging brain.
Reporting in the journal Neurochemistry International, researchers have found
that resveratrol activates an enzyme that helps make friendly NOS and can break
the plaque-formation cycle that is associated with the progression of
Alzheimer`s disease. The researchers were able to show that resveratrol
significantly inhibits plaque formation by as much as 90%.
TThe researchers concluded that their study "supports the concept that onset of
neurodegenerative disease may be delayed or mitigated with use of dietary
chemo-preventive agents that protect against beta-amyloid plaque formation and
oxidative stress." This evidence provides further support to the protective
nature of natural nutrients to prevent and halt the development of a host of
deadly chronic diseases.
Along with resveratrol, research has demonstrated the power of blueberries and
grape seed extract to lower the risks associated with brain aging and cognitive
decline. Each nutrient targets the expression of specific genes responsible for
the progression of dementia and memory-robbing illnesses. People with a familial
history of cognitive disease or early onset symptoms should consider
supplementing with 50 to 200 mg of resveratrol daily to prevent or reverse
amyloid plaque development.
Article References:br />
http://www.wellnessresources.com/he...
http://www.ncbi.nlm.nih.gov/pmc/art...
http://www.plosone.org/article/info...
http://www.ncbi.nlm.nih.gov/pubmed/...
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